- Approximately 600,000 people in
the United States live with tardive dyskinesia (TD), and about 65% have not yet been diagnosed1-3 - The diagnosis rate can be improved by increasing routine TD screenings in people treated with antipsychotic medication4
For seven consecutive years, TD Awareness Week – which occurs each year during Mental Health Awareness Month – has brought together the mental health advocacy community and states across the country to recognize the approximately 600,000 people in the
"TD Awareness Week increases dialogue around the physical, social and emotional consequences the uncontrollable movements of TD can have on individuals who are trying to manage their mental health," said
TD is a chronic condition that is unlikely to improve without treatment.1,4 The uncontrollable movements can affect one's ability to work, drive, walk, button a shirt or eat and drink and cause worry, frustration and self-consciousness.2,8-10 It is critical that people taking antipsychotic medication for mental illness be monitored by a healthcare provider for drug-induced movement disorders, such as TD.4,6 Routine screenings are essential for detection, proper diagnosis and appropriate management to help improve therapeutic outcomes.4
"The majority of people living with TD remain undiagnosed, reinforcing the importance of proactive recognition and treatment of the condition," said Eiry W. Roberts, M.D., Chief Medical Officer, Neurocrine Biosciences. "We are committed to partnering with all stakeholders during TD Awareness Week and beyond to advocate for routine screenings for patients at risk for TD."
The 2020 American Psychiatric Association Practice Guideline for the Treatment of Patients With Schizophrenia recommends screening for TD at least every six months in high-risk patients and at least every 12 months for others at risk of developing TD.4
To learn more about TD, living with TD and how to treat TD, visit TalkAboutTD.com.
About Tardive Dyskinesia Awareness Week
Since it began in 2018, all 50 states, Washington, D.C., and various mental health advocacy organizations have recognized the first full week of May as Tardive Dyskinesia (TD) Awareness Week, which acknowledges the approximately 600,000 Americans living with TD, an involuntary movement disorder associated with taking antipsychotic medication commonly prescribed to treat mental illnesses. Participants in TD Awareness Week help to educate people across
As part of Neurocrine Biosciences' commitment to TD education, more information is available at Neurocrine.com/TD-Awareness, and resources are available at TalkAboutTD.com. These resources can help patients and care partners understand TD and recognize its symptoms, request support and have a conversation with their healthcare provider about ways to manage their TD, including treatment options. Healthcare professionals can also visit MIND-TD.com to learn about differential diagnosis of TD and other movement disorders. For more information, follow and join the conversation online by sharing #TDAwarenessWeek #Screen4TD.
About Tardive Dyskinesia (TD)
Tardive dyskinesia (TD) is a movement disorder that is characterized by uncontrollable, abnormal and repetitive movements of the face, torso and/or other body parts, which may be disruptive and negatively impact patients. The condition is associated with taking certain kinds of mental health medicines (antipsychotics) that help control dopamine receptors in the brain. Taking antipsychotics commonly prescribed to treat mental illnesses such as major depressive disorder, bipolar disorder, schizophrenia and schizoaffective disorder, and other prescription medicines (metoclopramide and prochlorperazine) used to treat gastrointestinal disorders are associated with TD. In patients with TD, these treatments are thought to result in irregular dopamine signaling in a region of the brain that controls movement. The symptoms of TD can be severe and are often persistent and irreversible. TD is estimated to affect approximately 600,000 people in the United States.
About Neurocrine Biosciences, Inc.
References
- Cloud LJ, Zutshi D,
Factor SA . Tardive dyskinesia: therapeutic options for an increasingly common disorder. Neurotherapeutics. 2014;11(1):166-176. doi:10.1007/s13311-013-0222-5 - Data on file.
Neurocrine Biosciences, Inc. - Carbon M, Hsieh CH, Kane JM, Correll CU. Tardive dyskinesia prevalence in the period of second-generation antipsychotic use: a meta-analysis. J Clin Psychiatry. 2017;78(3):e264–e278. doi:10.4088/JCP.16r10832
- Keepers GA, Fochtmann LJ, Anzia JM, et al.
The American Psychiatric Association practice guideline for the treatment of patients with schizophrenia. Am J Psychiatry. 2020;177(9):868-872. doi:10.1176/appi.ajp.2020.177901 American Psychiatric Association . Diagnostic and Statistical Manual of Mental Disorders. 5th ed. Text Revision.American Psychiatric Association ; 2023.- Guy W. ECDEU Assessment Manual for Psychopharmacology.
National Institute of Mental Health ; 1976. - Caroff SN, Hurford I, Lybrand J, Campbell EC. Movement disorders induced by antipsychotic drugs: implications of the CATIE schizophrenia trial. Neurol Clin. 2011;29(1):127-148. doi:10.1016/j.ncl.2010.10.002
Task Force on Tardive Dyskinesia . Tardive dyskinesia: a task force report of theAmerican Psychiatric Association ; 1992.- Boumans CE, de Mooij KJ, Koch PA, van 't Hof MA, Zitman FG. Is the social acceptability of psychiatric patients decreased by orofacial dyskinesia? Schizophr Bull. 1994;20(2):339-344. doi:10.1093/schbul/20.2.339
- Yassa R. Functional impairment in tardive dyskinesia: medical and psychosocial dimensions. Acta Psychiatr Scand. 1989;80(1):64-67. doi:10.1111/j.1600-0447.1989.tb01301
- Increasing measurement-based assessment and care for people with serious mental illness.
Meadows Mental Health Policy Institute . PublishedJanuary 2024 . AccessedMarch 1, 2024 . https://mmhpi.org/project/increasing-measurement-based-assessment-and-care-for-people-with-serious-mental-illness/
© 2024
View original content to download multimedia:https://www.prnewswire.com/news-releases/neurocrine-biosciences-supports-tardive-dyskinesia-awareness-week-by-advocating-for-routine-screening-and-monitoring-302135994.html
SOURCE
Neurocrine Biosciences, Inc., Media, Aimee White, 1-858-354-7865, media@neurocrine.com; Investor, Todd Tushla, 1-858-617-7143, ir@neurocrine.com