"Most people living with tardive dyskinesia are already living with an underlying mental health condition, and their involuntary movements present additional physical, emotional and social challenges," said
Impact of Tardive Dyskinesia
A recent survey of patients with diagnosed or suspected TD (n=350) indicated that their movements impacted both their overall mental health and daily activities.5§ More than half of the patients surveyed felt that their mental health has been impacted by their involuntary movements (60%) and over two-thirds of patients reported that they were frustrated by their involuntary movements (69%).† According to the survey, patients with diagnosed or suspected TD reported the condition moderately, very or extremely affected them in the following areas:5‡ more than half said it affected their ability to sleep (51%) and nearly one-third said it impacted their ability to eat and drink (33%) and their ability to speak (30%).
"Tardive dyskinesia may impact people's overall mental health and cause a significant disruption to their daily lives, yet awareness of the condition remains low," said Eiry W. Roberts, M.D., Chief Medical Officer at
About Tardive Dyskinesia Awareness Week
Over the past four years, more than 40 states,
As part of
About Tardive Dyskinesia (TD)
Tardive dyskinesia (TD) is a movement disorder that is characterized by uncontrollable, abnormal and repetitive movements of the face, torso and/or other body parts, which may be disruptive and negatively impact patients. The condition is associated with taking certain kinds of mental health medicines (like antipsychotics) that help control dopamine receptors in the brain. Antipsychotics commonly prescribed to treat mental illnesses such as depression, bipolar disorder, schizophrenia and schizoaffective disorder, and certain medications to treat upset stomach, nausea and vomiting may also cause TD. In patients with TD, these treatments are thought to result in irregular dopamine signaling in a region of the brain that controls movement. The symptoms of TD can be severe and are often persistent and irreversible. TD is estimated to affect approximately 600,000 people in the U.S. For more information, visit www.TalkAboutTD.com.
About Neurocrine Biosciences
Neurocrine Biosciences is a neuroscience-focused, biopharmaceutical company dedicated to discovering, developing and delivering life-changing treatments for people with serious, challenging and under-addressed neurological, endocrine and psychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, Parkinson's disease, endometriosis*, uterine fibroids* and clinical programs in multiple therapeutic areas. For nearly three decades, Neurocrine Biosciences has specialized in targeting and interrupting disease-causing mechanisms involving the interconnected pathways of the nervous and endocrine systems. For more information, visit neurocrine.com, and follow the company on LinkedIn. (*in collaboration with AbbVie)
References
American Psychiatric Association . Diagnostic and Statistical Manual of Mental Disorders. 5th ed.American Psychiatric Association ; 2013:712.- Kenney C, Hunter C, Davidson A. Metaclopramide, an increasingly recognized cause of tardive dyskinesia. J Clin Pharmacol. 2008;48(3):379-384.
- Cloud LJ, Zutshi D,
Factor SA . Tardive dyskinesia: therapeutic options for an increasingly common disorder. Neurotherapeutics. 2014;11(1):166-176. - Ascher-Svanum H, Zhu B, Faries D, Peng X, Kinon BJ, Tohen M. Tardive dyskinesia and the 3-year course of schizophrenia: results from a large, prospective, naturalistic study. J Clin Psych. 2008;69(10):1580-1588
- Data on file.
Neurocrine Biosciences . - Data on file.
Neurocrine Biosciences .
§ Base: Patient ATU 2021. Target patients (diagnosed TD or suspected TD) n=350
† Responses based on survey question: To what extent is the physical impact of your involuntary movements frustrating? Rating scale: 1 to 5 where 1 means "not at all frustrating," and 5 means "extremely frustrating."
‡ Responses based on survey question: Since first experiencing involuntary movements, how has your ability to perform the following daily activities been affected, if at all? Rating scale: 1 to 5 when 1 means "not affected at all," and 5 means "extremely negatively affected."
View original content to download multimedia:http://www.prnewswire.com/news-releases/neurocrine-biosciences-supports-mental-health-month-and-tardive-dyskinesia-awareness-week-301281603.html
SOURCE
Neurocrine Biosciences, Michele Rest (Media), 858-617-7248, media@neurocrine.com; Todd Tushla (Investors), 858-617-7143, ir@neurocrine.com